SCHEMBL7767012

SCHEMBL7767012

NC(=O)c1ccc(Oc2ccc(N)cc2)cc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 6/20 0.59
ALDH1A1 P00352 6/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MAPT P10636 3/20 0.50
KMT2A Q03164 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 1/20 0.50
MITF O75030 1/20 0.50
GAA P10253 1/20 0.50
GFER P55789 1/20 0.50
NLRP1 Q9C000 1/20 0.50
NOD2 Q9HC29 1/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
PARP15 Q460N3 3/20 0.47
PARP14 Q460N5 2/20 0.47
PARP16 Q8N5Y8 1/20 0.47
PARP11 Q9NR21 1/20 0.47
PARP4 Q9UKK3 1/20 0.47
NR4A1 P22736 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27491890 0.88 PARP10 (0.58) PARP10ALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL2949574 0.86 PARP10 (0.59) PARP10ALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL7761855 0.85 MAOB (0.53) PARP10ALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL24750245 0.82 KDM4E (0.51) ALDH1A1HDAC3BRAFHDAC4HDAC1
SCHEMBL29938678 0.82 KDM4E (0.51) ALDH1A1HDAC3BRAFHDAC4HDAC1
SCHEMBL31557923 0.79 PARP10 (0.56) PARP10ALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL7409099 0.78 MAPT (0.48) ALDH1A1MAPTKMT2ATDP1MEN1
SCHEMBL28548362 0.78 PARP10 (0.54) PARP10ALDH1A1SMN1; SMN2MAPTKMT2A
Urea SCHEMBL28271688 0.78 PARP10 (0.75) PARP10ALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL148855 0.78 ALDH1A1 (0.53) PARP10ALDH1A1SMN1; SMN2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758665-B1 Polyimides and optical parts obtained by using the same HITACHI CHEMICAL CO LTD (JP) 2001-06-20 EP disclosed
US-5837804-A MULTILAYER POLYIMIDES FOR TRANSPARENCY AND OPTICAL WAVEGUIDES HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-11-17 US disclosed
EP-0758665-A1 Polyimides and optical parts obtained by using the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
EP-0308270-B1 Processes for preparation of polyimide-isoindoquinazoline dione and precursor thereof HITACHI CHEMICAL CO LTD (JP) 1993-12-08 EP disclosed
US-5115089-A Heat resistant polymers for electrical insulation, protective coatings for electronics formed by reaction of tetracarboxylic dianhydrides and diaminoamides and diamines HITACHI CHEMICAL CO., LTD. (JP) 1992-05-19 US disclosed
EP-0308270-A2 Processes for preparation of polyimide-isoindoquinazoline dione and precursor thereof Hitachi Chemical Co., Ltd. (JP) 1989-03-22 EP disclosed