Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.65 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.65 |
| ▸ | ANPEP | P15144 | 1/20 | 0.60 |
| ▸ | DPP4 | P27487 | 3/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7763478 | 0.99 | DPP8 (0.64) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL7321298 | 0.83 | ANPEP (0.71) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL7761836 | 0.81 | ANPEP (0.60) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL7318869 | 0.81 | ANPEP (0.68) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL17294044 | 0.81 | HDAC8 (0.49) | DPP8DPP7 | |
| SCHEMBL464672 | 0.81 | DPP8 (0.69) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL3703 | 0.81 | DPP8 (0.69) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL453671 | 0.81 | DPP8 (0.69) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL5816135 | 0.81 | DPP8 (0.69) | DPP8DPP7ANPEPDPP4DPP9 | |
| SCHEMBL3704 | 0.81 | DPP8 (0.69) | DPP8DPP7ANPEPDPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |