Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275292 | 0.94 | GAA (0.54) | GAABCL9CTNNB1F13A1ALDH1A1 | |
| SCHEMBL14275297 | 0.94 | GAA (0.54) | GAABCL9CTNNB1F13A1ALDH1A1 | |
| SCHEMBL6978503 | 0.83 | BCL9 (0.52) | GAABCL9CTNNB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7328515 | 0.82 | TDP1 (0.50) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL7338569 | 0.82 | TDP1 (0.50) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL28388872 | 0.78 | GAA (0.46) | GAABCL9CTNNB1F13A1ALDH1A1 | |
| SCHEMBL27818621 | 0.78 | MGLL (0.52) | GAABCL9CTNNB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27492526 | 0.76 | GAA (0.49) | GAABCL9CTNNB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27524001 | 0.76 | GAA (0.49) | GAABCL9CTNNB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28670395 | 0.76 | GAA (0.56) | GAABCL9CTNNB1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |