Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844764 | 1.00 | TSHR (0.55) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL15329266 | 0.84 | ALDH1A1 (0.46) | TSHRLMNACES2CES1ALDH1A1 | |
| SCHEMBL10343184 | 0.84 | DGKA (0.67) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL7950562 | 0.84 | DGKA (0.67) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL15044 | 0.84 | DGKA (0.67) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL94495 | 0.84 | DGKA (0.67) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL11864698 | 0.84 | DGKA (0.67) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL5586448 | 0.84 | DGKA (0.67) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL308404 | 0.84 | DGKA (0.67) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL22775305 | 0.84 | DGKA (0.67) | TSHRDGKALMNAPAMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576519-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2001-04-18 | — | — | EP | claimed |