Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.67 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758416 | 1.00 | HRH3 (0.67) | HRH3HRH4KDM4EALDH1A1LMNA | |
| SCHEMBL7763017 | 0.83 | HRH3 (0.59) | HRH3HRH4KDM4EALDH1A1HPGD | |
| SCHEMBL14032674 | 0.82 | HRH3 (0.68) | HRH3HRH4KDM4EALDH1A1LMNA | |
| SCHEMBL8232974 | 0.82 | HRH4 (0.60) | HRH3HRH4KDM4EKMT2AHPGD | |
| SCHEMBL14032664 | 0.80 | HRH3 (0.65) | HRH3HRH4KDM4EALDH1A1LMNA | |
| SCHEMBL13726832 | 0.77 | HPGD (0.60) | HRH3HRH4ALDH1A1LMNAKMT2A | |
| SCHEMBL8244556 | 0.77 | HRH3 (0.54) | HRH3HRH4ALDH1A1LMNAKMT2A | |
| SCHEMBL25740940 | 0.77 | GAA (0.58) | HRH3HRH4KDM4EALDH1A1GAA | |
| SCHEMBL13727922 | 0.77 | GAA (0.58) | HRH3HRH4KDM4EALDH1A1GAA | |
| SCHEMBL16254956 | 0.77 | GAA (0.58) | HRH3HRH4KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085728-A2 | ANTIBACTERIAL CHIRAL 8-(SUBSTITUTED PIPERIDINO)-BENZO [I, J] QUINOLIZINES, PROCESSES, COMPOSITIONS AND METHODS OF TREATMENT | WOCKHARDT LIMITED (IN) | 2001-11-15 | — | — | WO | disclosed |