Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762072 | 0.83 | HRH3 (0.67) | HRH3HRH4ALDH1A1HPGDS1PR5 | |
| SCHEMBL7758416 | 0.83 | HRH3 (0.67) | HRH3HRH4ALDH1A1HPGDS1PR5 | |
| SCHEMBL492424 | 0.79 | HRH3 (0.75) | HRH3HRH4ALDH1A1S1PR5SMN1; SMN2 | |
| SCHEMBL491078 | 0.79 | HRH3 (0.75) | HRH3HRH4ALDH1A1S1PR5SMN1; SMN2 | |
| SCHEMBL15033036 | 0.75 | MEN1 (0.47) | HRH3ALDH1A1S1PR5 | |
| SCHEMBL15171874 | 0.75 | HRH3 (0.61) | HRH3HRH4ALDH1A1 | |
| SCHEMBL22422459 | 0.75 | SIGMAR1 (0.51) | HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL4024651 | 0.75 | SMN1; SMN2 (0.65) | HRH3HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL3456613 | 0.75 | PLA2G1B (0.64) | ALDH1A1HPGD | |
| SCHEMBL10502710 | 0.75 | ALDH1A1 (0.52) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085728-A2 | ANTIBACTERIAL CHIRAL 8-(SUBSTITUTED PIPERIDINO)-BENZO [I, J] QUINOLIZINES, PROCESSES, COMPOSITIONS AND METHODS OF TREATMENT | WOCKHARDT LIMITED (IN) | 2001-11-15 | — | — | WO | disclosed |