Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413800 | 0.73 | CCR6 (0.52) | SMN1; SMN2FOLH1 | |
| SCHEMBL413898 | 0.72 | CCR6 (0.51) | SMN1; SMN2SIRT2SIRT1MEN1ALDH1A1 | |
| SCHEMBL14999593 | 0.72 | ATM (0.46) | CA1CA2MEN1KMT2A | |
| SCHEMBL416891 | 0.72 | CCR6 (0.48) | SMN1; SMN2SIRT2SIRT1MEN1ALDH1A1 | |
| SCHEMBL10954785 | 0.71 | TGM2 (0.60) | SMN1; SMN2CA1CA2MMP2MMP9 | |
| SCHEMBL6558520 | 0.71 | CA1 (0.51) | SMN1; SMN2CA1CA2ALDH1A1 | |
| SCHEMBL2453446 | 0.70 | HTT (0.60) | SMN1; SMN2CA1CA2MMP2MMP9 | |
| SCHEMBL23000174 | 0.69 | CA2 (0.50) | CA1CA2MEN1KMT2A | |
| SCHEMBL20553378 | 0.69 | CA2 (0.50) | CA1CA2MEN1KMT2A | |
| SCHEMBL3445880 | 0.68 | HTT (0.62) | SMN1; SMN2CA1CA2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100806-A1 | ERYTHROMYCIN DERIVATIVE WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006586-A1 | ERYTHROMYCIN DERIVATIVE WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2000-02-10 | — | — | WO | disclosed |