Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329856 | 1.00 | GPR84 (0.47) | GPR84FFAR1FFAR4TP53PSMD14 | |
| SCHEMBL6651738 | 0.92 | TP53 (0.38) | GPR84FFAR1FFAR4TP53NFKB1 | |
| SCHEMBL11329852 | 0.87 | GPR84 (0.48) | GPR84FFAR1FFAR4TP53PSMD14 | |
| SCHEMBL28275845 | 0.85 | GPR84 (0.47) | GPR84FFAR1FFAR4TP53PSMD14 | |
| Ammonia Solution, Strong SCHEMBL29078532 | 0.85 | LMNA (0.39) | GPR84FFAR1FFAR4TP53 | |
| SCHEMBL2382843 | 0.84 | CA12 (0.41) | TP53 | |
| Methylamine SCHEMBL29052659 | 0.84 | TP53 (0.41) | GPR84FFAR1FFAR4TP53 | |
| SCHEMBL20590005 | 0.84 | FFAR4 (0.49) | GPR84FFAR1FFAR4NFKB1 | |
| SCHEMBL11440897 | 0.84 | FFAR4 (0.49) | GPR84FFAR1FFAR4NFKB1 | |
| SCHEMBL12479666 | 0.84 | FFAR4 (0.49) | GPR84FFAR1FFAR4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001091716-A1 | PERORAL THERAPEUTIC SYSTEM COMPRISING GLIPIZIDE | ADD ADVANCED DRUG DELIVERY TECHNOLOGIES AG (CH) | 2001-12-06 | — | — | WO | disclosed |
| US-4992278-A | Cellulose casing, core containing hydrophilic polymeric swelling agent blend of vinyl acetate-vinylpyrrolidone copolymer asnd polyoxyethylene glycol | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |