Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.45 |
| ▸ | MMP3 | P08254 | 8/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762293 | 1.00 | MMP2 (0.45) | MMP2MMP3MMP12MMP1 | |
| SCHEMBL7762305 | 1.00 | MMP2 (0.45) | MMP2MMP3MMP12MMP1 | |
| SCHEMBL6279996 | 0.92 | MMP2 (0.53) | MMP2MMP3MMP12MMP1 | |
| SCHEMBL6279998 | 0.92 | MMP2 (0.53) | MMP2MMP3MMP12MMP1 | |
| SCHEMBL7765135 | 0.85 | MME (0.37) | MMP2MMP3 | |
| SCHEMBL7765130 | 0.85 | MME (0.37) | MMP2MMP3 | |
| SCHEMBL7765144 | 0.85 | MME (0.37) | MMP2MMP3 | |
| SCHEMBL7765152 | 0.85 | MMP2 (0.55) | MMP2MMP3MMP12MMP1 | |
| SCHEMBL7763746 | 0.82 | MMP2 (0.49) | MMP2MMP3MMP12MMP1 | |
| SCHEMBL7763742 | 0.82 | MMP2 (0.49) | MMP2MMP3MMP12MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | claimed |
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | disclosed |