Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.55 |
| ▸ | MMP3 | P08254 | 8/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763742 | 0.95 | MMP2 (0.49) | MMP2MMP3MMP12MMP1MMP7 | |
| SCHEMBL7763746 | 0.95 | MMP2 (0.49) | MMP2MMP3MMP12MMP1MMP7 | |
| SCHEMBL7758513 | 0.90 | MMP12 (0.62) | MMP2MMP3MMP12MMP1MMP7 | |
| SCHEMBL7758518 | 0.90 | MMP12 (0.62) | MMP2MMP3MMP12MMP1MMP7 | |
| SCHEMBL7763651 | 0.85 | MMP2 (0.59) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL7763650 | 0.85 | MMP2 (0.59) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL7762298 | 0.85 | MMP2 (0.45) | MMP2MMP3MMP12MMP1 | |
| SCHEMBL7762305 | 0.85 | MMP2 (0.45) | MMP2MMP3MMP12MMP1 | |
| SCHEMBL7762293 | 0.85 | MMP2 (0.45) | MMP2MMP3MMP12MMP1 | |
| SCHEMBL6270662 | 0.83 | MMP2 (0.65) | MMP2MMP3MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | claimed |