Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778896 | 0.84 | PTPN1 (0.45) | PTPN1SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL775707 | 0.79 | TP53 (0.41) | SMN1; SMN2LMNAHPGDRAB9AGAA | |
| SCHEMBL775687 | 0.75 | SOAT1 (0.44) | LMNARAB9AMAPK1POLB | |
| SCHEMBL774744 | 0.75 | SOAT1 (0.44) | LMNARAB9AMAPK1POLB | |
| SCHEMBL7218828 | 0.66 | PTPN1 (0.46) | PTPN1SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL13188044 | 0.65 | HPGD (0.41) | PTPN1SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL8016937 | 0.65 | KDM4E (0.35) | SMN1; SMN2LMNAHPGDRAB9AGAA | |
| SCHEMBL21765873 | 0.64 | PTPN1 (0.88) | PTPN1SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL13178829 | 0.64 | PTPN1 (0.68) | PTPN1SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL776272 | 0.62 | PTPN1 (0.45) | PTPN1SMN1; SMN2LMNAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |