Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774571 | 0.89 | SOAT1 (0.42) | LMNAMAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL774744 | 0.88 | SOAT1 (0.44) | LMNAMAPK1RAB9APOLB | |
| SCHEMBL775687 | 0.88 | SOAT1 (0.44) | LMNAMAPK1RAB9APOLB | |
| SCHEMBL774641 | 0.83 | TP53 (0.43) | TP53ALDH1A1THRBMEN1LMNA | |
| SCHEMBL776246 | 0.79 | PTPN1 (0.42) | ALDH1A1LMNAMAPK1MAPTKDM4E | |
| SCHEMBL775558 | 0.73 | SOAT1 (0.43) | LMNAMAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL776835 | 0.72 | SOAT1 (0.46) | LMNARAB9ACA1CA2POLB | |
| SCHEMBL774986 | 0.72 | SOAT1 (0.46) | LMNARAB9ACA1CA2POLB | |
| SCHEMBL23871973 | 0.70 | TP53 (0.43) | TP53ALDH1A1THRBMEN1LMNA | |
| SCHEMBL8016937 | 0.69 | KDM4E (0.35) | TP53ALDH1A1LMNAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |