Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775687 | 1.00 | SOAT1 (0.44) | SOAT1CETPHSP90AA1DEGS1LMNA | |
| SCHEMBL774571 | 0.99 | SOAT1 (0.42) | SOAT1CETPHSP90AA1DEGS1LMNA | |
| SCHEMBL776835 | 0.85 | SOAT1 (0.46) | SOAT1CETPHSP90AA1DEGS1LMNA | |
| SCHEMBL774986 | 0.85 | SOAT1 (0.46) | SOAT1CETPHSP90AA1DEGS1LMNA | |
| SCHEMBL775558 | 0.84 | SOAT1 (0.43) | SOAT1CETPHSP90AA1DEGS1LMNA | |
| SCHEMBL776246 | 0.75 | PTPN1 (0.42) | LMNAPOLBRAB9AMAPK1 | |
| SCHEMBL27358463 | 0.74 | CETP (0.43) | SOAT1CETPHSP90AA1DEGS1LMNA | |
| SCHEMBL24465104 | 0.71 | NPC1 (0.40) | SOAT1CETPHSP90AA1DEGS1LMNA | |
| SCHEMBL12726010 | 0.70 | DEGS1 (0.51) | SOAT1CETPHSP90AA1DEGS1LMNA | |
| SCHEMBL14292212 | 0.70 | GAA (0.43) | POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |