Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PNLIP | P16233 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762889 | 0.80 | MAPT (0.61) | LMNAMAPTKMT2AMEN1USP2 | |
| SCHEMBL13852930 | 0.77 | PARP1 (0.53) | LMNAMAPTKMT2AMEN1PNLIP | |
| SCHEMBL7067826 | 0.76 | MEN1 (0.71) | LMNAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL8052698 | 0.75 | KMT2A (0.69) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL28213376 | 0.75 | KMT2A (0.68) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL27754112 | 0.74 | NPC1 (0.73) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8974371 | 0.74 | MEN1 (0.55) | LMNAKMT2AMEN1POLBMITF | |
| SCHEMBL7921365 | 0.74 | CTNNB1 (0.56) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL7755868 | 0.72 | LMNA (0.51) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL11114394 | 0.72 | CTNNB1 (0.54) | LMNAMAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070189-A1 | METHOD AND COMPOSITION FOR SKIN LIGHTENING APPLYING CARBOXYLIC ACIDS | UNILEVER PLC (GB) | 2001-09-27 | — | — | WO | disclosed |