Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29211143 | 0.83 | KMT2A (0.61) | MAPTLMNAKMT2AUSP2MEN1 | |
| SCHEMBL7762884 | 0.80 | LMNA (0.57) | MAPTLMNAKMT2AUSP2MEN1 | |
| SCHEMBL4432153 | 0.78 | MAPT (0.69) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL8052702 | 0.77 | KMT2A (0.63) | MAPTLMNAKMT2AUSP2MEN1 | |
| SCHEMBL2700947 | 0.77 | RAB9A (0.62) | MAPTLMNAKMT2AUSP2MEN1 | |
| SCHEMBL5049435 | 0.75 | SGMS2 (0.64) | MAPTLMNAKMT2AUSP2MEN1 | |
| SCHEMBL15285774 | 0.75 | MAPT (0.65) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6408304 | 0.74 | MEN1 (0.69) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL10192623 | 0.74 | KMT2A (0.68) | MAPTLMNAKMT2AUSP2MEN1 | |
| SCHEMBL11794672 | 0.74 | KMT2A (0.64) | MAPTLMNAKMT2AUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070189-A1 | METHOD AND COMPOSITION FOR SKIN LIGHTENING APPLYING CARBOXYLIC ACIDS | UNILEVER PLC (GB) | 2001-09-27 | — | — | WO | disclosed |