Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756527 | 0.74 | RXRA (0.49) | RXRA | |
| SCHEMBL7761638 | 0.71 | RXRA (0.47) | MEN1KMT2ARXRA | |
| SCHEMBL8736175 | 0.68 | RXRA (0.36) | RXRA | |
| SCHEMBL2877333 | 0.68 | — | — | |
| SCHEMBL9418276 | 0.67 | TP53 (0.57) | TP53CYP1A2MEN1TNNI3TNNT2 | |
| SCHEMBL3087767 | 0.67 | — | — | |
| SCHEMBL25673 | 0.63 | SLC6A4 (0.31) | — | |
| SCHEMBL379632 | 0.63 | ESR1 (0.34) | L3MBTL1 | |
| SCHEMBL6567713 | 0.62 | PGR (0.34) | L3MBTL1 | |
| SCHEMBL26071850 | 0.62 | TP53 (0.62) | TP53CYP1A2MEN1TNNI3TNNT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915823-B1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CT INTERNAT DE (FR) | 2001-04-18 | — | — | EP | disclosed |