Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | BRS3 | P32247 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CDK7 | P50613 | 2/20 | 0.44 |
| ▸ | CCNH | P51946 | 2/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | UQCRB | P14927 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367349 | 0.79 | KMT2A (0.52) | KMT2AMAPTMAPK1POLBSMN1; SMN2 | |
| SCHEMBL22928148 | 0.74 | BRS3 (0.44) | KMT2ACYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL22928030 | 0.74 | BRS3 (0.44) | KMT2ACYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL678551 | 0.73 | CA1 (0.65) | KMT2ACDK1CCNB1CCNA2CDK2 | |
| SCHEMBL22928040 | 0.72 | UQCRB (0.51) | KMT2ACYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL7761716 | 0.72 | MAPT (0.53) | KMT2ACYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL13935835 | 0.72 | UQCRB (0.49) | CYP1A2CYP3A4MAPTMAPK1CYP2C19 | |
| SCHEMBL4403147 | 0.72 | NR3C2 (0.54) | CYP1A2CYP3A4MAPTMAPK1CYP2C19 | |
| SCHEMBL15603554 | 0.71 | FFAR1 (0.72) | KMT2ACYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL22928033 | 0.71 | CDK1 (0.50) | KMT2ACYP1A2CYP3A4MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | disclosed |