Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592360 | 0.75 | PKM (0.52) | KMT2ATP53PKMMAPTMEN1 | |
| SCHEMBL16205824 | 0.74 | KMT2A (0.41) | KMT2ATP53PKMMAPTMEN1 | |
| SCHEMBL1690514 | 0.73 | HTR6 (0.72) | KMT2ATP53PKMMAPTMEN1 | |
| SCHEMBL7902370 | 0.72 | PTGS1 (0.59) | KMT2ATP53PKMMAPTMEN1 | |
| SCHEMBL8458647 | 0.72 | ADRA2A (0.57) | KMT2ATP53PKMMAPTMEN1 | |
| SCHEMBL8269562 | 0.71 | TP53 (0.64) | KMT2ATP53PKMMAPTMEN1 | |
| SCHEMBL24000629 | 0.70 | MAPT (0.55) | KMT2ATP53PKMMAPTMEN1 | |
| SCHEMBL9616551 | 0.70 | MAPT (0.54) | TP53MAPT | |
| SCHEMBL8366960 | 0.70 | MAPT (0.52) | KMT2ATP53PKMMAPTMEN1 | |
| SCHEMBL8366958 | 0.70 | KIT (0.50) | KMT2ATP53PKMMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512006-B1 | Novel 3-position Nitrogen substituted 6,6- disubstituted-5, 6-dihydropyrones and related compounds possess antiviral properties | WARNER-LAMBERT COMPANY | 2003-01-28 | — | — | US | disclosed |