Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACAT2 | Q9BWD1 | 1/20 | 0.37 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763001 | 1.00 | GRIN2B (0.54) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL7763107 | 0.76 | GRIN2B (0.47) | GRIN2BGRIN1IDO1CYP3A4 | |
| SCHEMBL11588057 | 0.75 | TAAR1 (0.59) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL4023670 | 0.73 | TAAR1 (0.73) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL5068041 | 0.72 | TAAR1 (0.66) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL4797248 | 0.70 | TAAR1 (0.64) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL7104418 | 0.70 | TAAR1 (0.49) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL7760203 | 0.70 | TAAR1 (0.49) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL7104421 | 0.70 | TAAR1 (0.49) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL7765310 | 0.70 | TAAR1 (0.53) | GRIN2BTAAR1IDO1PNMTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531702-B1 | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-subst. -5-(trifluoromethyl)pyrrole compounds from N-(subst. benzyl)-2,2,2-trifluoroacetimidoyl chloride compounds | BASF AG (DE) | 2001-05-30 | — | — | EP | disclosed |
| EP-0531702-A1 | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substitued-5-(trifluoromethyl)pyrrole compounds from N-(substituted benzyl)-2,2,2-trifluoroacetimidoyl chloride compounds | AMERICAN CYANAMID COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5145986-A | Process for the manufacture of insecticidal, nematicidal and acaricidal 2-aryl-3-substituted-5-(trifluoromethyl)pyrrole compounds from N-(substituted benzyl)-2,2,2-trifluoro-acetimidoyl chloride compounds | AMERICAN CYANAMID COMPANY (US) | 1992-09-08 | — | — | US | disclosed |