SCHEMBL776312

SCHEMBL776312

CCCC(=O)N[C@@H]1CCCC[C@H]1NC(=O)CCC

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.48
TRPV1 Q8NER1 4/20 0.47
CNR1 P21554 2/20 0.47
CNR2 P34972 2/20 0.47
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CTSD P07339 1/20 0.43
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775241 0.96 L3MBTL1 (0.48) L3MBTL1TRPV1CNR1CNR2ALDH1A1
SCHEMBL29315233 0.92 PSEN1 (0.46) L3MBTL1TRPV1CNR1CNR2ALDH1A1
SCHEMBL22402479 0.91 L3MBTL1 (0.42) L3MBTL1TRPV1CNR1CNR2ALDH1A1
SCHEMBL22858735 0.88 TRPV1 (0.50) L3MBTL1TRPV1CNR1CNR2SMN1; SMN2
SCHEMBL4341647 0.88 TRPV1 (0.50) L3MBTL1TRPV1CNR1CNR2SMN1; SMN2
SCHEMBL30526487 0.88 TRPV1 (0.50) L3MBTL1TRPV1CNR1CNR2SMN1; SMN2
SCHEMBL12555494 0.88 TRPV1 (0.58) TRPV1CNR1CNR2SMN1; SMN2HDAC3
SCHEMBL13870528 0.86 TRPV1 (0.66) TRPV1CNR1CNR2SMN1; SMN2
SCHEMBL777541 0.86 TRPV1 (0.66) TRPV1CNR1CNR2SMN1; SMN2
SCHEMBL22858805 0.84 TRPV1 (0.50) L3MBTL1TRPV1CNR1CNR2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673998-B2 Polymer compositions with improved cold flow BRIDGESTONE CORPORATION (JP) 2014-03-18 US disclosed
US-20120071583-A1 POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW BRIDGESTONE CORPORATION (JP) 2012-03-22 US disclosed