Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.50 |
| ▸ | CNR1 | P21554 | 8/20 | 0.50 |
| ▸ | CNR2 | P34972 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341647 | 1.00 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1SMN1; SMN2 | |
| SCHEMBL30526487 | 1.00 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1SMN1; SMN2 | |
| SCHEMBL22859155 | 0.96 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1 | |
| SCHEMBL22858805 | 0.96 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1 | |
| SCHEMBL4342108 | 0.96 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1 | |
| SCHEMBL30526484 | 0.89 | TRPV1 (0.60) | TRPV1CNR1CNR2SMN1; SMN2 | |
| SCHEMBL22858818 | 0.89 | TRPV1 (0.53) | TRPV1CNR1CNR2L3MBTL1 | |
| SCHEMBL776312 | 0.88 | L3MBTL1 (0.48) | TRPV1CNR1CNR2L3MBTL1SMN1; SMN2 | |
| SCHEMBL30526486 | 0.88 | TRPV1 (0.68) | TRPV1CNR1CNR2SMN1; SMN2 | |
| SCHEMBL4135884 | 0.86 | TRPV1 (0.71) | TRPV1CNR1CNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021000925-A1 | PYRROLO [2, 3-b] PYRAZINES AS HPK1 INHIBITOR AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2021-01-07 | — | — | WO | disclosed |