Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29441331 | 0.77 | RAB9A (0.49) | RAB9AGAASMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL1074961 | 0.76 | ALDH1A1 (0.56) | RAB9AGAASMN1; SMN2TSHRCYP2D6 | |
| Hydrochloric Acid SCHEMBL29381203 | 0.74 | RAB9A (0.54) | RAB9AGAASMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL9533233 | 0.74 | RAB9A (0.46) | RAB9AGAASMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL946805 | 0.74 | RAB9A (0.46) | RAB9AGAASMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL1892162 | 0.74 | RAB9A (0.54) | RAB9AGAASMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL16954 | 0.72 | F2 (0.58) | SMN1; SMN2TSHRF2F10F12 | |
| Benzoic Acid SCHEMBL16963066 | 0.72 | TSHR (0.58) | RAB9AGAASMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL3070522 | 0.71 | SMN1; SMN2 (0.44) | RAB9AGAASMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL5640920 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10973819-B2 | Small molecules inhibitors of RAD51 | THE UNIVERSITY OF CHICAGO (US) | 2021-04-13 | — | — | US | disclosed |
| US-20190083491-A1 | SMALL MOLECULES INHIBITORS OF RAD51 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-03-21 | — | — | US | disclosed |
| WO-2013039413-A1 | MONO-AND POLYNUCLEAR BORON IMINOPYPROLYL COMPLEXES: METHODS OF PREPARATION AND USE AS LUMINESCENT MATERIALS | INSTITUTO SUPERIOR TECNICO (PT) | 2013-03-21 | — | — | WO | disclosed |
| EP-1110999-A2 | Stabilizing mixtures for organic polymers | Great Lakes Chemical (Europe) GmbH (CH) | 2001-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190083491-A1 | SMALL MOLECULES INHIBITORS OF RAD51 | RAD51, MRE11, DDB1 | RAB9A 1629/4885GAA 4713/4885SMN1; SMN2 1326/4885 |
| US-10973819-B2 | Small molecules inhibitors of RAD51 | RAD51, MRE11, DDB1 | RAB9A 1629/4885GAA 4713/4885SMN1; SMN2 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.