Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.45 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL7762804 | 0.95 | MMP9 (0.45) | MMP9MMP8MMP14CPB2GNPAT | |
| SCHEMBL7759040 | 0.87 | CPB2 (0.46) | CPB2GNPATERAP2LNPEPKMT2A | |
| SCHEMBL5587642 | 0.87 | MMP9 (0.63) | MMP9MMP8MMP14KMT2APYGL | |
| SCHEMBL14513403 | 0.87 | MMP9 (0.63) | MMP9MMP8MMP14KMT2APYGL | |
| SCHEMBL7759027 | 0.86 | CPB2 (0.50) | MMP8CPB2GNPATERAP2LNPEP | |
| SCHEMBL7762775 | 0.85 | CPB2 (0.49) | CPB2GNPATERAP2LNPEPKMT2A | |
| SCHEMBL7761873 | 0.85 | GNPAT (0.52) | CPB2GNPATERAP2LNPEPECE1 | |
| SCHEMBL7206070 | 0.83 | MMP9 (0.59) | MMP9MMP8MMP14PYGL | |
| SCHEMBL7206063 | 0.83 | MMP9 (0.59) | MMP9MMP8MMP14PYGL | |
| Hydrochloric Acid SCHEMBL7205259 | 0.83 | MMP9 (0.51) | MMP9MMP8MMP14PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |