SCHEMBL7763569

SCHEMBL7763569

O=C(O)CN(CP(=O)(O)O)C(=O)NO

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ENO1 P06733 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
BLM P54132 1/20 0.34
KMT2A Q03164 1/20 0.34
EYA2 O00167 1/20 0.30
APP P05067 1/20 0.30
ACE P12821 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6794530 0.79 TDP1 (0.40) TDP1MEN1LMNAHPGDTSHR
SCHEMBL7876936 0.79 TDP1 (0.46) ENO1TDP1MEN1LMNAHPGD
SCHEMBL249304 0.75 TDP1 (0.37) TDP1MEN1LMNAHPGDTSHR
SCHEMBL7875291 0.74 MVD (0.33) TDP1MEN1LMNAHPGDTSHR
SCHEMBL11324627 0.73 PHF8 (0.39) TDP1MEN1LMNAHPGDTSHR
SCHEMBL2988195 0.72 TDP1 (0.34) TDP1MEN1LMNAHPGDTSHR
SCHEMBL8967699 0.71 MEN1 (0.33) TDP1MEN1LMNAHPGDTSHR
SCHEMBL4750608 0.71 MEN1 (0.33) TDP1MEN1LMNAHPGDTSHR
SCHEMBL11314817 0.69 TSHR (0.33) TDP1MEN1LMNAHPGDTSHR
SCHEMBL4750605 0.69 MEN1 (0.32) TDP1MEN1LMNAHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001094358-A1 ORGANOPHOSPHOROUS HYDROXAMIC ACID DERIVATIVES USED AS HERBICIDES JOMAA PHARMAKA GMBH (DE) 2001-12-13 WO disclosed