Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774870 | 0.96 | RAB9A (0.42) | HPGDTAS1R3TAS1R1CYP3A4CYP2C19 | |
| SCHEMBL19538672 | 0.89 | PSEN1 (0.36) | HPGDTAS1R3TAS1R1TAS1R2CYP3A4 | |
| SCHEMBL11890370 | 0.83 | RAB9A (0.54) | HPGDCYP3A4CYP2C19RAB9AALDH1A1 | |
| SCHEMBL20340486 | 0.82 | ALDH1A1 (0.37) | HPGDTAS1R3TAS1R1TAS1R2CYP3A4 | |
| SCHEMBL6430011 | 0.79 | USP2 (0.40) | HPGDCYP3A4CYP2C19RAB9AALDH1A1 | |
| SCHEMBL11890375 | 0.79 | RAB9A (0.58) | HPGDCYP3A4CYP2C19RAB9AALDH1A1 | |
| SCHEMBL18199497 | 0.78 | RAB9A (0.49) | HPGDCYP3A4CYP2C19RAB9AEPHX1 | |
| SCHEMBL5067337 | 0.78 | RAB9A (0.49) | HPGDCYP3A4CYP2C19RAB9AEPHX1 | |
| SCHEMBL1076528 | 0.78 | HPGD (0.35) | HPGDTAS1R3TAS1R1TAS1R2CYP3A4 | |
| SCHEMBL8241745 | 0.78 | EPHX1 (0.58) | HPGDCYP3A4CYP2C19RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |