SCHEMBL7763663

SCHEMBL7763663

O=P(O)(O)C(C(O)(c1cccnc1)c1cccnc1)P(=O)(O)O

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 11/20 0.51
FDPS P14324 5/20 0.46
KCNH2 Q12809 6/20 0.46
BTN3A1 O00481 1/20 0.45
PDE3A Q14432 1/20 0.45
CYP19A1 P11511 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13746036 0.77 FDPS (0.53) KCNA5FDPSBTN3A1PDE3ACYP19A1
SCHEMBL15533205 0.76 FDPS (0.53) KCNA5FDPSBTN3A1PDE3ACYP19A1
SCHEMBL4725467 0.75 FDPS (0.51) KCNA5FDPSBTN3A1PDE3ACYP19A1
SCHEMBL20148789 0.74 CYP3A4 (0.62) KCNA5KCNH2CYP19A1
SCHEMBL9850885 0.71 LMNA (0.51) FDPSBTN3A1PDE3ACYP19A1
SCHEMBL11594033 0.71 FDPS (0.47) KCNA5FDPSBTN3A1PDE3ACYP19A1
SCHEMBL15038326 0.71 FDPS (0.47) KCNA5FDPSBTN3A1PDE3ACYP19A1
SCHEMBL19627972 0.71 CYP19A1 (0.57) KCNA5CYP19A1
SCHEMBL11624747 0.70 KCNA5 (0.61) KCNA5KCNH2
Water SCHEMBL29532583 0.70 LMNA (0.50) FDPSBTN3A1PDE3ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001082903-A1 ENTERIC COATED FORMULATION OF BISPHOSPHONIC ACID COMPOUNDS AND ASSOCIATED THERAPEUTIC METHODS LIPOCINE, INC. (US) 2001-11-08 WO disclosed