Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | INSR | P06213 | 4/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7104941 | 0.89 | MAPT (0.46) | MAPTINSRAPPKMT2AHTT | |
| Hydrochloric Acid SCHEMBL11528454 | 0.80 | MAPT (0.47) | MAPTINSRAPPKMT2AHTT | |
| SCHEMBL14194559 | 0.77 | MAPT (0.44) | MAPTINSRAPPKMT2AHTT | |
| Iodide SCHEMBL8072633 | 0.74 | MEN1 (0.35) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL8745629 | 0.72 | MEN1 (0.36) | MAPTKMT2AHTTMEN1LMNA | |
| Iodide SCHEMBL8745044 | 0.72 | MEN1 (0.43) | MAPTINSRAPPKMT2AHTT | |
| SCHEMBL22189127 | 0.69 | MAPT (0.48) | MAPTINSRAPPKMT2AHTT | |
| SCHEMBL8080557 | 0.68 | MAPT (0.69) | MAPTINSRAPPKMT2AHTT | |
| SCHEMBL8080554 | 0.68 | MAPT (0.69) | MAPTINSRAPPKMT2AHTT | |
| SCHEMBL13046317 | 0.68 | MAPT (0.69) | MAPTINSRAPPKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708334-B1 | Reagent and method for analyzing solid components in urine | SYSMEX CORP (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0613003-B1 | A reagent for detecting malaria infected cells and a detecting method for malaria infected cells using the same | SYSMEX CORP (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891733-A | COMPRISING A BUFFER AGENT, AN OSMOTIC PRESSURE COMPENSATING AGENT,A FIRST DYE WHICH IS A CONDENSED BENZENE DERIVATIVE, A SECOND FLUORESCENT DYE, AND A CHELATING AGENT | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0708334-A2 | Reagent and method for analyzing solid components in urine | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5470751-A | Reagent for detecting malaria infected cells and a detecting method for malaria infected cells using the same | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0613003-A1 | A reagent for detecting malaria infected cells and a detecting method for malaria infected cells using the same | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |