SCHEMBL8745629

SCHEMBL8745629

CC[n+]1c(C(=Cc2ccccc2)N(C)C)cccc1C(=Cc1ccccc1)N(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NR1I2 O75469 1/20 0.34
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
AKR1C3 P42330 1/20 0.33
KDM1A O60341 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RECQL P46063 1/20 0.33
CYP2D6 P10635 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 2/20 0.32
MAPT P10636 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NPC1 O15118 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
FBP1 P09467 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL8072633 0.98 MEN1 (0.35) MEN1KMT2ANR1I2LMNAALDH1A1
SCHEMBL17911707 0.81 MEN1 (0.40) MEN1KMT2ANR1I2LMNAALDH1A1
Iodide SCHEMBL5229857 0.80 MEN1 (0.42) MEN1KMT2ANR1I2LMNAALDH1A1
SCHEMBL7544937 0.75 CHAT (0.35) ALDH1A1TSHRAKR1C3KDM1AMAPT
SCHEMBL7904469 0.75 ESR1 (0.45) MEN1KMT2AALDH1A1TSHRAKR1C3
SCHEMBL2845203 0.75 AKR1C1 (0.45) MEN1KMT2ALMNAALDH1A1TSHR
Iodide SCHEMBL3807575 0.74 CHAT (0.37) MEN1KMT2AALDH1A1TSHRAKR1C3
SCHEMBL8745599 0.74 MEN1 (0.32) MEN1KMT2ANR1I2LMNAALDH1A1
Iodide SCHEMBL8745570 0.73 MEN1 (0.33) MEN1KMT2ALMNAALDH1A1RECQL
Hydrochloric Acid SCHEMBL11314920 0.73 MEN1 (0.31) MEN1KMT2ALMNAALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499693-B1 Method of differentiating erythroblasts from other cells by flow cytometry TOA MEDICAL ELECTRONICS (JP) 1997-02-05 EP claimed
EP-0513762-B1 Reagent and method for analyzing cells in urine TOA MEDICAL ELECTRONICS (JP) 1996-09-04 EP claimed
EP-0483116-B1 Method of classifying leukocytes by flow cytometry and reagents used in the method TOA MEDICAL ELECTRONICS (JP) 1996-07-17 EP claimed
EP-0485945-B1 Method of classifying leukocytes by flow cytometry TOA MEDICAL ELECTRONICS (JP) 1996-06-05 EP claimed
EP-0268766-B1 METHOD OF CLASSIFYING LEUKOCYTES BY FLOW CYTOMETRY AND REAGENTS USED IN THE METHOD TOA MEDICAL ELECTRONICS CO., LTD. (JP) 1993-06-16 EP claimed
EP-0259834-B1 METHOD OF CLASSIFYING LEUCOCYTES BY FLOW CYTOMETRY TOA MEDICAL ELECTRONICS CO., LTD. (JP) 1992-08-12 EP claimed