Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.75 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.75 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.75 |
| ▸ | GC | P02774 | 1/20 | 0.75 |
| ▸ | PGR | P06401 | 1/20 | 0.75 |
| ▸ | RXRA | P19793 | 1/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.75 |
| ▸ | CNR1 | P21554 | 1/20 | 0.75 |
| ▸ | HTR2C | P28335 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.75 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763268 | 1.00 | VDR (0.75) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL7764237 | 0.90 | VDR (0.81) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL7764783 | 0.90 | VDR (0.81) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL7760573 | 0.90 | VDR (0.81) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL6846636 | 0.88 | VDR (0.68) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL23359068 | 0.87 | VDR (0.86) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL11165113 | 0.87 | VDR (0.86) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL9722601 | 0.87 | VDR (0.86) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL10892402 | 0.87 | VDR (0.86) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL9722603 | 0.87 | VDR (0.86) | VDRMAPTADORA3SLC6A2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854138-B1 | Vitamin D3 derivative and production process thereof | TEIJIN LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-6177586-B1 | USEFUL AS A PHARMACEUTICAL SUCH AS AN AGENT FOR PROMOTING BONE FORMATION, AN AGENT FOR SUPPRESSING PROLIFERATION OF TUMOR CELLS, AN AGENT FOR HIGH CALCIUM BLOOD DISEASES, AND AN IMMUNOSUPPRESSION AGENT | TEIJIN LIMITED (JP) | 2001-01-23 | — | — | US | disclosed |
| EP-0854138-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0712843-A1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |