Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063906 | 0.82 | HTR2A (0.44) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL9772360 | 0.82 | HTR2A (0.44) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL7954422 | 0.82 | HTR2A (0.44) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL17559139 | 0.82 | HTR2A (0.44) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL17835702 | 0.82 | HTR2A (0.44) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL30832970 | 0.79 | KCNE1 (0.37) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL2444502 | 0.79 | KCNE1 (0.37) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL5730688 | 0.77 | HTR2A (0.40) | HTR2AHTR2CHTR2BHRH3MMP1 | |
| SCHEMBL7761032 | 0.75 | SIGMAR1 (0.48) | SIGMAR1DRD2DRD3 | |
| SCHEMBL9772397 | 0.73 | SLC18A3 (0.50) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860439-B1 | Process for preparing an optically active phenylglycidyl acid derivative | DSM NV (NL) | 2001-06-13 | — | — | EP | disclosed |
| US-6025506-A | Process for preparing an optically active phenylglycidyl acid derivative | DSM N.V. (NL) | 2000-02-15 | — | — | US | disclosed |
| EP-0860439-A1 | Process for preparing an optically active phenylglycidyl acid derivative | DSM N.V. (NL) | 1998-08-26 | — | — | EP | disclosed |