Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7760971 | 0.87 | CSNK1E (0.40) | CSNK1EALDH1A1CYSLTR2CYSLTR1LIPG | |
| Hydrochloric Acid SCHEMBL8720793 | 0.87 | CSNK1E (0.40) | CSNK1EALDH1A1CYSLTR2CYSLTR1LIPG | |
| Hydrochloric Acid SCHEMBL7764448 | 0.87 | CSNK1E (0.40) | CSNK1EALDH1A1CYSLTR2CYSLTR1LIPG | |
| Sulfuric Acid SCHEMBL7765900 | 0.86 | TP53 (0.44) | CSNK1EALDH1A1CYSLTR2CYSLTR1LIPG | |
| Acetic Acid SCHEMBL7764520 | 0.86 | ALDH1A1 (0.44) | CSNK1EALDH1A1CYSLTR2CYSLTR1PRSS1 | |
| Succinic Acid SCHEMBL7764851 | 0.83 | CYSLTR2 (0.50) | ALDH1A1CYSLTR2CYSLTR1CES2CES1 | |
| Malonic Acid SCHEMBL7763542 | 0.83 | CYSLTR2 (0.44) | CSNK1EALDH1A1CYSLTR2CYSLTR1CNR2 | |
| Lactic Acid SCHEMBL7768244 | 0.83 | CSNK1E (0.43) | CSNK1EALDH1A1CYSLTR2CYSLTR1CNR2 | |
| Adipic Acid SCHEMBL7765945 | 0.82 | CYSLTR2 (0.52) | ALDH1A1CYSLTR2CYSLTR1MEN1KMT2A | |
| Cadaverine Tartrate SCHEMBL7764354 | 0.82 | CSNK1E (0.42) | CSNK1EALDH1A1CYSLTR2CYSLTR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825175-B1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0825175-A1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |