Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.39 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL7764354 | 0.93 | CSNK1E (0.42) | CSNK1EGPR84FFAR1ALDH1A1CYSLTR2 | |
| Acetic Acid SCHEMBL7764520 | 0.92 | ALDH1A1 (0.44) | CSNK1EALDH1A1CYSLTR2CYSLTR1CNR2 | |
| Succinic Acid SCHEMBL7764851 | 0.89 | CYSLTR2 (0.50) | FFAR1ALDH1A1CYSLTR2CYSLTR1 | |
| Malonic Acid SCHEMBL7763542 | 0.89 | CYSLTR2 (0.44) | CSNK1EALDH1A1CYSLTR2CYSLTR1ASAH1 | |
| Adipic Acid SCHEMBL7765945 | 0.88 | CYSLTR2 (0.52) | GPR84FFAR1ALDH1A1CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL7760971 | 0.87 | CSNK1E (0.40) | CSNK1EALDH1A1CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL7764448 | 0.87 | CSNK1E (0.40) | CSNK1EALDH1A1CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL8720793 | 0.87 | CSNK1E (0.40) | CSNK1EALDH1A1CYSLTR2CYSLTR1 | |
| Sulfuric Acid SCHEMBL7765900 | 0.86 | TP53 (0.44) | CSNK1EALDH1A1CYSLTR2CYSLTR1 | |
| Lactic Acid SCHEMBL7768220 | 0.86 | GPR84 (0.45) | GPR84FFAR1ACE2MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825175-B1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0825175-A1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |