Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25170030 | 0.87 | TDP1 (0.53) | TDP1L3MBTL1GPR35HPGDTSHR | |
| SCHEMBL3503761 | 0.87 | TDP1 (0.53) | TDP1L3MBTL1GPR35HPGDTSHR | |
| SCHEMBL23302690 | 0.86 | TDP1 (0.47) | TDP1L3MBTL1GPR35HPGDTSHR | |
| SCHEMBL2071280 | 0.81 | TDP1 (0.64) | TDP1L3MBTL1GPR35HPGDTSHR | |
| SCHEMBL793527 | 0.81 | ALDH1A1 (0.61) | TDP1L3MBTL1GPR35HPGDTSHR | |
| SCHEMBL2873852 | 0.80 | TDP1 (0.50) | TDP1L3MBTL1GPR35HPGDTSHR | |
| SCHEMBL3052893 | 0.80 | TDP1 (0.50) | TDP1L3MBTL1GPR35HPGDTSHR | |
| SCHEMBL2873855 | 0.80 | TDP1 (0.50) | TDP1L3MBTL1GPR35HPGDTSHR | |
| SCHEMBL11854478 | 0.80 | TDP1 (0.49) | TDP1L3MBTL1GPR35HPGDTSHR | |
| SCHEMBL793981 | 0.80 | TDP1 (0.49) | TDP1L3MBTL1GPR35HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775693-B1 | Process for the preparation of 2-amino-6-chlorophenyl-isopropylsulfide | BAYER AG (DE) | 2001-06-13 | — | — | EP | claimed |