Malonic Acid

Malonic Acid

SCHEMBL7764463

CCCCCCCCCCCC[N+](C)(C)Cc1cccc(C[N+](C)(C)CCCCCCCCCCCC)c1.O=C([O-])CC(=O)[O-]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.59
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
TP53 P04637 1/20 0.57
MAPK1 P28482 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HTT P42858 3/20 0.56
PSMD14 O00487 1/20 0.48
HSP90AA1 P07900 1/20 0.48
MMP2 P08253 1/20 0.48
MC4R P32245 1/20 0.48
RAD52 P43351 1/20 0.48
GPR84 Q9NQS5 2/20 0.42
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL7764870 0.92 DNM1 (0.59) DNM1MEN1KMT2ATP53MAPK1
Acetic Acid SCHEMBL7764392 0.92 DNM1 (0.62) DNM1MEN1KMT2ATP53MAPK1
Adipic Acid SCHEMBL7760680 0.90 DNM1 (0.57) DNM1MEN1KMT2ATP53MAPK1
Malonic Acid SCHEMBL7765990 0.88 DNM1 (0.61) DNM1MEN1KMT2ATP53MAPK1
Acetic Acid SCHEMBL7764398 0.87 DNM1 (0.69) DNM1MEN1KMT2ATP53MAPK1
Cadaverine Tartrate SCHEMBL7764909 0.86 DNM1 (0.60) DNM1MEN1KMT2ATP53MAPK1
L-Lactic Acid SCHEMBL7768066 0.86 DNM1 (0.56) DNM1MEN1KMT2ATP53MAPK1
Hydrochloric Acid SCHEMBL8722911 0.85 KMT2A (0.77) DNM1MEN1KMT2ATP53MAPK1
Hydrochloric Acid SCHEMBL7760760 0.85 KMT2A (0.77) DNM1MEN1KMT2ATP53MAPK1
Hydrochloric Acid SCHEMBL7766070 0.85 KMT2A (0.77) DNM1MEN1KMT2ATP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825175-B1 Quaternary ammonium disinfectant NICCA CHEMICAL CO (JP) 2001-06-13 EP disclosed
EP-0825175-A1 Quaternary ammonium disinfectant NICCA CHEMICAL CO., LTD. (JP) 1998-02-25 EP disclosed