Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL7760680 | 0.96 | DNM1 (0.57) | DNM1MEN1KMT2ATP53MAPK1 | |
| Malonic Acid SCHEMBL7764463 | 0.92 | DNM1 (0.59) | DNM1MEN1KMT2ATP53MAPK1 | |
| Acetic Acid SCHEMBL7764392 | 0.92 | DNM1 (0.62) | DNM1MEN1KMT2ATP53MAPK1 | |
| Benzododecinium SCHEMBL17435033 | 0.90 | DNM1 (0.74) | DNM1MEN1KMT2ATP53MAPK1 | |
| Succinic Acid SCHEMBL7768274 | 0.88 | DNM1 (0.61) | DNM1MEN1KMT2ATP53MAPK1 | |
| Benzododecinium SCHEMBL17435029 | 0.88 | DNM1 (0.70) | DNM1MEN1KMT2ATP53MAPK1 | |
| Acetic Acid SCHEMBL7764398 | 0.87 | DNM1 (0.69) | DNM1MEN1KMT2ATP53MAPK1 | |
| Cadaverine Tartrate SCHEMBL7764909 | 0.86 | DNM1 (0.60) | DNM1MEN1KMT2ATP53MAPK1 | |
| L-Lactic Acid SCHEMBL7768066 | 0.86 | DNM1 (0.56) | DNM1MEN1KMT2ATP53MAPK1 | |
| Miristalkonium Ion SCHEMBL17435024 | 0.86 | DNM1 (0.72) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825175-B1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0825175-A1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |