Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768360 | 0.85 | GLA (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6322890 | 0.77 | NPC1 (0.40) | RAB9ANPC1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6322888 | 0.77 | NPC1 (0.40) | RAB9ANPC1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7530250 | 0.76 | F2 (0.35) | RAB9ANPC1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL7768591 | 0.75 | CNR2 (0.33) | RAB9ASMN1; SMN2NR3C1LMNAMEN1 | |
| SCHEMBL6320347 | 0.74 | POLB (0.49) | SMN1; SMN2ALDH1A1TSHRADRA2BADRA2C | |
| SCHEMBL6320349 | 0.74 | POLB (0.49) | SMN1; SMN2ALDH1A1TSHRADRA2BADRA2C | |
| SCHEMBL7609951 | 0.72 | SMN1; SMN2 (0.36) | RAB9ANPC1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6027885 | 0.71 | SMN1; SMN2 (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7611484 | 0.70 | ALDH1A1 (0.38) | RAB9ANPC1SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |