Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764630 | 0.85 | RAB9A (0.32) | GLASMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL6323870 | 0.77 | POLB (0.43) | GLASMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL6323867 | 0.77 | POLB (0.43) | GLASMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL6319153 | 0.71 | SMN1; SMN2 (0.48) | SMN1; SMN2NPY5RMTORNPC1RAB9A | |
| SCHEMBL6319157 | 0.71 | SMN1; SMN2 (0.48) | SMN1; SMN2NPY5RMTORNPC1RAB9A | |
| SCHEMBL7768358 | 0.70 | ADRB1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6320365 | 0.70 | HTT (0.53) | SMN1; SMN2POLBMTORNPC1RAB9A | |
| SCHEMBL6320371 | 0.70 | HTT (0.53) | SMN1; SMN2POLBMTORNPC1RAB9A | |
| SCHEMBL6322165 | 0.68 | SMN1; SMN2 (0.46) | GLASMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL6322166 | 0.68 | SMN1; SMN2 (0.46) | GLASMN1; SMN2POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |