Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610419 | 0.86 | KMT2A (0.54) | CNR2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL7613185 | 0.81 | RAB9A (0.53) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7612159 | 0.80 | RAB9A (0.46) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL7605257 | 0.80 | KMT2A (0.41) | CNR2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL7612545 | 0.80 | CASR (0.46) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7768377 | 0.79 | SMN1; SMN2 (0.48) | CNR2KMT2AMEN1MITFALDH1A1 | |
| SCHEMBL7610407 | 0.79 | GLA (0.48) | KMT2AMEN1OPRM1ALDH1A1LMNA | |
| SCHEMBL9662279 | 0.79 | LMNA (0.71) | KMT2AMEN1OPRM1OPRD1MITF | |
| Hydrochloric Acid SCHEMBL7764617 | 0.78 | KMT2A (0.46) | CNR2KMT2AMEN1OPRM1OPRD1 | |
| Sulfuric Acid SCHEMBL7540439 | 0.75 | SMN1; SMN2 (0.44) | CNR2KMT2AMEN1MITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |