Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413727 | 0.74 | KDM4E (0.33) | KDM4E | |
| SCHEMBL8746464 | 0.69 | GABRP (0.31) | — | |
| SCHEMBL29037188 | 0.67 | MEN1 (0.45) | KMT2A | |
| SCHEMBL9236631 | 0.67 | KDM4E (0.35) | KMT2AKDM4EMAPT | |
| SCHEMBL7043226 | 0.66 | KDM4E (0.53) | KMT2AKDM4EMAPT | |
| SCHEMBL2352572 | 0.66 | FOS (0.36) | KMT2AKDM4E | |
| SCHEMBL9240767 | 0.66 | PDE10A (0.32) | — | |
| SCHEMBL2637729 | 0.66 | SMN1; SMN2 (0.41) | KMT2AKDM4EMAPT | |
| SCHEMBL27566292 | 0.66 | KDM4E (0.36) | KMT2AKDM4EMAPT | |
| SCHEMBL10695297 | 0.66 | NTRK1 (0.36) | KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018374-B2 | Crystal of amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-04-28 | — | — | US | disclosed |
| EP-2583967-B1 | CRYSTAL OF AMIDE COMPOUND | TAKEDA PHARMACEUTICAL (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-20130252954-A2 | CRYSTAL OF AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-09-26 | — | — | US | disclosed |
| EP-2583967-A1 | CRYSTAL OF AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2013-04-24 | — | — | EP | disclosed |
| US-20130090337-A1 | CRYSTAL OF AMIDE COMPOUND | KITAYAMA MASATO (JP) | 2013-04-11 | — | — | US | disclosed |
| EP-1112271-A1 | ERGOLINE AMINE DERIVATIVES WITH BLOOD PRESSURE LOWERING EFFECT | Cybio Screening GmbH (DE) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000004018-A1 | ERGOLINE AMINE DERIVATIVES WITH BLOOD PRESSURE LOWERING EFFECT | CYBIO SCREENING GMBH (DE) | 2000-01-27 | — | — | WO | disclosed |