Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.78 |
| ▸ | MMP2 | P08253 | 6/20 | 0.78 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898960 | 0.88 | MMP13 (1.00) | MMP13MMP2FPR2PROKR1MMP12 | |
| SCHEMBL8361681 | 0.86 | MMP13 (0.78) | MMP13MMP2FPR2PROKR1SMN1; SMN2 | |
| SCHEMBL5898984 | 0.82 | MMP13 (1.00) | MMP13MMP2FPR2PROKR1MMP12 | |
| SCHEMBL5898947 | 0.78 | MMP13 (0.70) | MMP13MMP2FPR2PROKR1SMN1; SMN2 | |
| SCHEMBL7414533 | 0.77 | MMP13 (0.56) | MMP13MMP2FPR2PROKR1SMN1; SMN2 | |
| SCHEMBL5898977 | 0.77 | MMP13 (1.00) | MMP13MMP2FPR2PROKR1SMN1; SMN2 | |
| SCHEMBL5898973 | 0.77 | MMP13 (1.00) | MMP13MMP2FPR2PROKR1SMN1; SMN2 | |
| SCHEMBL5898969 | 0.77 | MMP13 (0.82) | MMP13MMP2FPR2PROKR1SMN1; SMN2 | |
| SCHEMBL8361683 | 0.77 | MMP13 (0.76) | MMP13MMP2FPR2PROKR1SMN1; SMN2 | |
| SCHEMBL7076681 | 0.76 | ACLY (0.60) | MMP13MMP2FPR2PROKR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085680-A2 | SULFONYL ARYL OR HETEROARYL HYDROXAMIC ACID COMPOUNDS | PHARMACIA CORPORATION (US) | 2001-11-15 | — | — | WO | disclosed |