Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764888 | 0.92 | CRBN (0.43) | CRBNCYP2C19GBA1KMT2ACYP1A2 | |
| SCHEMBL7762185 | 0.91 | CRBN (0.42) | CRBNCYP2C19GBA1KMT2ACYP1A2 | |
| SCHEMBL7767198 | 0.89 | CRBN (0.49) | CRBNCYP2C19KMT2ACYP2C9L3MBTL1 | |
| SCHEMBL7762186 | 0.75 | POLB (0.41) | CRBNCYP2C19KMT2ACYP1A2CYP2C9 | |
| SCHEMBL20395688 | 0.73 | CYP1A2 (0.42) | CRBNCYP2C19GBA1CYP1A2CYP3A4 | |
| SCHEMBL15178943 | 0.73 | CYP2C19 (0.47) | CRBNCYP2C19GBA1KMT2ACYP1A2 | |
| SCHEMBL7769294 | 0.73 | CRBN (0.42) | CRBNKMT2AL3MBTL1NPC1GAA | |
| SCHEMBL7767445 | 0.73 | CRBN (0.42) | CRBNCYP2C19KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7764873 | 0.72 | CYP2C19 (0.41) | CRBNCYP2C19GBA1CYP1A2CYP3A4 | |
| SCHEMBL7765802 | 0.72 | CRBN (0.54) | CRBNKMT2ACYP2C9GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |