Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766827 | 0.92 | CYP2C19 (0.39) | CYP2C19GBA1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7765770 | 0.91 | CYP2C19 (0.38) | CYP2C19GBA1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7766815 | 0.87 | CRBN (0.43) | CYP2C19CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20395688 | 0.75 | CYP1A2 (0.42) | CYP2C19GBA1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7764999 | 0.74 | ALDH1A1 (0.37) | CYP2C19CYP1A2CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL7764865 | 0.72 | CRBN (0.45) | CYP2C19GBA1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL15178943 | 0.72 | CYP2C19 (0.47) | CYP2C19GBA1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7764884 | 0.71 | CRBN (0.36) | SMN1; SMN2CRBN | |
| SCHEMBL7764957 | 0.71 | CRBN (0.48) | CYP3A4ALDH1A1SMN1; SMN2CRBN | |
| SCHEMBL8396285 | 0.68 | KAT2A (0.39) | CYP1A2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |