Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SDCBP | O00560 | 1/20 | 0.33 |
| ▸ | SDC2 | P34741 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767198 | 0.77 | CRBN (0.49) | CRBNAGTR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL7767445 | 0.75 | CRBN (0.42) | CRBNAGTR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL7764884 | 0.74 | CRBN (0.36) | CRBNACES100A4MAPTSDCBP | |
| SCHEMBL7764865 | 0.73 | CRBN (0.45) | CRBNAGTR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL7766806 | 0.72 | CRBN (0.40) | CRBNAGTR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL7764888 | 0.71 | CRBN (0.43) | CRBNMAPTKMT2AL3MBTL1MEN1 | |
| SCHEMBL7767450 | 0.71 | CRBN (0.41) | CRBNAGTR2MAPTKMT2AL3MBTL1 | |
| SCHEMBL7762185 | 0.70 | CRBN (0.42) | CRBNMAPTKMT2AL3MBTL1MEN1 | |
| SCHEMBL4699124 | 0.67 | CRBN (0.54) | CRBNMAPTKMT2AL3MBTL1NPC1 | |
| SCHEMBL7762186 | 0.67 | POLB (0.41) | CRBNMAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |