Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.54 |
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA4 | P22748 | 4/20 | 0.49 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | MC3R | P41968 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203011 | 0.86 | MEN1 (0.66) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22023393 | 0.80 | TDP1 (0.72) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1953503 | 0.80 | TDP1 (0.61) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7444522 | 0.79 | MAPT (0.68) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7859 | 0.79 | HDAC1 (0.72) | TDP1NPC1RAB9AKMT2AALOX5 | |
| Hydrochloric Acid SCHEMBL23062929 | 0.77 | HDAC1 (0.69) | TDP1NPC1RAB9AKMT2AALOX5 | |
| Hydrochloric Acid SCHEMBL30882658 | 0.77 | HDAC1 (0.69) | TDP1NPC1RAB9AKMT2AALOX5 | |
| Hydrochloric Acid SCHEMBL30882401 | 0.77 | HDAC1 (0.69) | TDP1NPC1RAB9AKMT2AALOX5 | |
| SCHEMBL1285919 | 0.77 | MAPT (0.70) | TDP1NPC1RAB9AALOX5HDAC3 | |
| Water SCHEMBL28210512 | 0.77 | HDAC1 (0.69) | TDP1NPC1RAB9AKMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | claimed |