Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15689485 | 0.84 | FDPS (0.45) | FDPSSLC6A3MAPK1ALOX15PKM | |
| SCHEMBL6748509 | 0.75 | FDPS (0.41) | FDPSCYP3A4SLC6A3MAPK1ALOX15 | |
| SCHEMBL6142897 | 0.75 | FDPS (0.65) | FDPSSLC6A3ALDH1A1TSHRCYP2C19 | |
| SCHEMBL1276911 | 0.71 | — | — | |
| SCHEMBL3109516 | 0.70 | — | — | |
| SCHEMBL12811609 | 0.68 | FDPS (0.40) | FDPSCYP3A4SLC6A3MAPK1PKM | |
| SCHEMBL9933616 | 0.67 | FDPS (0.54) | FDPSCYP3A4SLC6A3MAPK1ALOX15 | |
| SCHEMBL6959399 | 0.67 | HTT (0.46) | FDPSCYP3A4MAPK1PKMALDH1A1 | |
| SCHEMBL2091120 | 0.67 | FDPS (0.39) | FDPSCYP3A4SLC6A3MAPK1PKM | |
| SCHEMBL244256 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103180-A2 | Hydroxyphenylvinylthiazoles | Ciba SC Holding AG (CH) | 2001-05-30 | — | — | EP | disclosed |