Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026681 | 0.80 | FDPS (0.61) | FDPSSLC6A3ALDH1A1CYP2C19TSHR | |
| SCHEMBL514756 | 0.79 | FDPS (1.00) | FDPSSLC6A3ALDH1A1 | |
| Phosphoric Acid SCHEMBL6547515 | 0.76 | FDPS (0.56) | FDPSSLC6A3ALDH1A1CYP2C19TSHR | |
| SCHEMBL7765082 | 0.75 | FDPS (0.46) | FDPSSLC6A3ALDH1A1CYP2C19TSHR | |
| SCHEMBL9933616 | 0.75 | FDPS (0.54) | FDPSSLC6A3ALDH1A1 | |
| SCHEMBL15689485 | 0.73 | FDPS (0.45) | FDPSSLC6A3ALDH1A1TSHR | |
| SCHEMBL6547517 | 0.72 | FDPS (0.51) | FDPSSLC6A3ALDH1A1 | |
| SCHEMBL10709303 | 0.71 | FDPS (0.50) | FDPS | |
| SCHEMBL167744 | 0.70 | — | — | |
| SCHEMBL244256 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014072930-A2 | FUSED PYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-05-15 | — | — | WO | disclosed |
| EP-1103180-B1 | Hydroxyphenylvinylthizoles | CIBA SC HOLDING AG (CH) | 2005-01-12 | — | — | EP | disclosed |
| US-6624182-B1 | Method for the treatment of surfaces comprising applying to these surfaces an antimicrobially effective amount of a hydroxyphenylvinyl thiazole of formula antimicrobial, deodorisation and disinfection of the skin, mucosa and hair | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | disclosed |
| EP-1103180-A2 | Hydroxyphenylvinylthiazoles | Ciba SC Holding AG (CH) | 2001-05-30 | — | — | EP | disclosed |
| US-5470859-A | Cognition activators for the central nervous system | BEECHAM GROUP P.L.C. (GB) | 1995-11-28 | — | — | US | disclosed |
| EP-0414394-B1 | Azabicyclic Derivatives having muscarinic receptor affinity | BEECHAM GROUP PLC (GB) | 1995-07-05 | — | — | EP | disclosed |
| EP-0414394-A2 | Azabicyclic Derivatives having muscarinic receptor affinity | BEECHAM GROUP PLC (GB) | 1991-02-27 | — | — | EP | disclosed |