Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 4/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592014 | 0.82 | PDE4D (0.42) | HCAR2DAOLMNAALPLALPG | |
| SCHEMBL2360470 | 0.81 | HCAR2 (0.52) | HCAR2DAOLMNACCNA2CDK2 | |
| SCHEMBL5772385 | 0.80 | MAPK1 (0.36) | HCAR2LMNAALPLCSNK2A2KDR | |
| SCHEMBL8521461 | 0.79 | MAPK1 (0.35) | HCAR2ALPLMAPK1GAAMAPT | |
| SCHEMBL3261591 | 0.73 | — | — | |
| SCHEMBL14715589 | 0.73 | ALDH1A1 (0.49) | LMNAMAPK1RAB9ANPC1POLB | |
| SCHEMBL12767758 | 0.70 | HCAR2 (0.48) | HCAR2DAOLMNACCNA2CDK2 | |
| SCHEMBL3624738 | 0.69 | MAPK1 (0.67) | HCAR2DAOLMNAALPLCSNK2A2 | |
| SCHEMBL6654827 | 0.69 | KDM4E (0.38) | LMNAMAPK1CYP2C19GAASMN1; SMN2 | |
| SCHEMBL3261563 | 0.68 | BTK (0.41) | HCAR2DAOCCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749448-B1 | USE OF PYRAZOLE-BLOCKED POLYISOCYANATES IN ONE-COMPONENT CLEAR COATINGS | ARCO CHEM TECH (US) | 2001-05-30 | — | — | EP | claimed |