Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677892 | 0.85 | ALDH1A1 (0.39) | PDE4DALDH1A1SOAT1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7765129 | 0.82 | HCAR2 (0.44) | HCAR2DAOSMN1; SMN2MAPTLMNA | |
| SCHEMBL10964577 | 0.81 | HCAR3 (0.45) | PDE4DHCAR2ALDH1A1SOAT1L3MBTL1 | |
| SCHEMBL2360470 | 0.78 | HCAR2 (0.52) | HCAR2DAOALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3164864 | 0.74 | ALDH1A1 (0.41) | PDE4DALDH1A1SOAT1SMN1; SMN2KDM4E | |
| SCHEMBL2725056 | 0.74 | — | — | |
| SCHEMBL7102277 | 0.72 | ALDH1A1 (0.40) | PDE4DALDH1A1SOAT1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7973627 | 0.72 | ALDH1A1 (0.48) | ALDH1A1SOAT1L3MBTL1MAPTLMNA | |
| SCHEMBL1665229 | 0.71 | DAO (0.58) | PDE4DHCAR2DAOALDH1A1SMN1; SMN2 | |
| SCHEMBL12767758 | 0.71 | HCAR2 (0.48) | HCAR2DAOALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138280-A2 | HERBICIDE/SAFENER COMBINATIONS COMPRISING ARYLPYRIDAZINONES AND SAFENER | BAYER CROPSCIENCE AG (DE) | 2011-11-10 | — | — | WO | claimed |
| EP-2092824-A1 | Heterocyclyl pyrimidines | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |