Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13500312 | 0.84 | PARG (0.56) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL10282879 | 0.82 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL634085 | 0.79 | ALDH1A1 (0.79) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL6820712 | 0.77 | ATM (0.58) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL12169331 | 0.75 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL12279884 | 0.74 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL12279267 | 0.74 | EGFR (0.55) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL15726889 | 0.74 | CNR2 (0.45) | TSHRMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL15199346 | 0.74 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL8389751 | 0.73 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100785-A1 | SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES | Aventis CropScience GmbH (DE) | 2001-05-23 | — | — | EP | disclosed |
| US-6197729-B1 | COMBATING PEST WHICH COMPRISES APPLYING TO PEST OR ITS LOCUS PESTICIDAL CYCLOHEXYLAMINOPYRIMIDINNE COMPOUND | HOECHST SCHERING AGREVO (DE) | 2001-03-06 | — | — | US | disclosed |
| WO-2000007998-A1 | SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |