Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078402 | 0.84 | CA1 (0.48) | ALDH1A1SMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL28393150 | 0.83 | ATM (0.50) | ALDH1A1GAASMN1; SMN2CA1CA2 | |
| SCHEMBL634085 | 0.80 | ALDH1A1 (0.79) | ALDH1A1GAASMN1; SMN2CA1CA2 | |
| SCHEMBL23583261 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2CA1CA2 | |
| SCHEMBL3071850 | 0.77 | KIF11 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11252176 | 0.77 | LMNA (0.52) | ALDH1A1GAASMN1; SMN2CA1CA2 | |
| SCHEMBL25241499 | 0.76 | ALDH1A1 (0.47) | ALDH1A1GAASMN1; SMN2CA1CA2 | |
| SCHEMBL15199346 | 0.76 | ALDH1A1 (0.57) | ALDH1A1GAASMN1; SMN2CA1CA2 | |
| SCHEMBL13500312 | 0.74 | PARG (0.56) | ALDH1A1GAASMN1; SMN2CA1CA2 | |
| SCHEMBL3160804 | 0.74 | ALDH1A1 (0.56) | ALDH1A1GAASMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523904-B1 | Process for preparing azetidin-2-one derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0487343-B1 | Process for preparing a lithographic plate | FUJI PHOTO FILM CO LTD (JP) | 1999-04-28 | — | — | EP | disclosed |
| US-5322939-A | Process for preparing azetidin-2-one derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0523904-A1 | Process for preparing azetidin-2-one derivatives | Takasago International Corporation (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0487343-A1 | Process for preparing a lithographic plate | Fuji Photo Film Co., Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |